Diet, Drugs, and Dopamine
The New Science of Achieving a Healthy Weight
Failed to add items
Add to Cart failed.
Add to Wish List failed.
Remove from wishlist failed.
Adding to library failed
Follow podcast failed
Unfollow podcast failed
Get 2 free audiobooks during trial.
Pre-order for $15.39
No default payment method selected.
We are sorry. We are not allowed to sell this product with the selected payment method
-
Narrated by:
-
Hillary Huber
About this listen
From the New York Times bestselling author of The End of Overeating comes an illuminating understanding of body weight, including the promise—and peril —of the latest weight loss drugs.
The struggle is universal: we work hard to lose weight, only to find that it slowly creeps back. In America, body weight has become a pain point shrouded in self-recrimination and shame, not to mention bias from the medical community. For many, this battle not only takes a mental toll but also becomes a physical threat: three-quarters of American adults struggle with weight-related health conditions, including high blood pressure, heart disease, and diabetes. We know that diets don’t work, and yet we also know that excess weight starves us of years and quality of life. Where do we go from here?
In Diet, Drugs, and Dopamine, former FDA Commissioner Dr. David A. Kessler unpacks the mystery of weight in the most comprehensive work to date on this topic, giving listeners the power to dramatically improve their health. Kessler, who has himself struggled with weight, suggests the new class of GLP-1 weight loss drugs have provided a breakthrough: they have radically altered our understanding of weight loss. They make lasting change possible, but they also have real disadvantages and must be considered as part of a comprehensive approach together with nutrition, behavior, and physical activity.
Critical to this new perspective is the insight that weight-loss drugs act on the part of the brain that is responsible for cravings. In essence, the drugs tamp down the addictive circuits that overwhelm rational decision-making and quiet the “food noise” that distracts us. Identifying these mechanisms allows us to develop a strategy for effective long-term weight loss, and that begins with naming the elephant in the room: ultraformulated foods are addictive. Losing weight is a process of treating addiction.
In this landmark book, one of the nation’s leading public health officials breaks taboos around this fraught conversation, giving listeners the tools to unplug the brain’s addictive wiring and change their relationship with food. Dr. Kessler cautions that drugs, on their own, pose serious risks and are not a universal solution. But with this new understanding of the brain-body feedback loop comes new possibilities for our health and freedom from a lifelong struggle.
Eye-opening, provocative, and rigorous, this book is a must-hear for anyone who has ever struggled to maintain their weight—which is to say, everyone.
©2025 David A. Kessler (P)2025 Macmillan AudioCritic reviews
"Who could be better suited and more trustworthy than former FDA commissioner Dr. David A. Kessler to doggedly sort through the scientific evidence, cut through the hype, and bring us to a better understanding of our own body weight? Diet, Drugs, and Dopamine is eye-opening, beautifully crafted, full of practical insights, and a great read."—Abraham Verghese, New York Times bestselling author of The Covenant of Water
"A brilliant and incisive examination of one of our country's most vexing health challenges. Dr. Kessler's sharp scientific analysis cuts through the fog of confusion surrounding weight loss and offers a practical, sustainable pathway to better health. It is no surprise he is one of the great medical and public health leaders of our time."—Vivek H. Murthy, MD, 19th and 21st Surgeon General of the United States and New York Times bestselling author of Together
“Diet, Drugs, and Dopamine is a tour de force and reflects a clarity of thinking on many controversial issues from food restricting to intuitive eating, body positivity to toxic fat, and GLP-1 agonists as a possible revolutionary tool to combat obesity. There’s even a section on menopause! This book is the definitive scientific source on food addiction."—Anna Lembke, MD, New York Times bestselling author of Dopamine Nation
Related to this topic
-
The Let Them Theory
- A Life-Changing Tool That Millions of People Can’t Stop Talking About
- By: Mel Robbins
- Narrated by: Mel Robbins
- Length: 10 hrs and 38 mins
- Unabridged
-
Overall
-
Performance
-
Story
In her latest groundbreaking book, The Let Them Theory, Mel Robbins—New York Times bestselling author and one of the world's most respected experts on motivation, confidence, and mindset—teaches you how to stop wasting energy on what you can't control and start focusing on what truly matters: YOU. Your happiness. Your goals. Your life.
-
-
“…Grant me the serenity…”
- By Rachel Cornell on 12-25-24
By: Mel Robbins
-
The 5 Second Rule
- Transform your Life, Work, and Confidence with Everyday Courage
- By: Mel Robbins
- Narrated by: Mel Robbins
- Length: 7 hrs and 35 mins
- Unabridged
-
Overall
-
Performance
-
Story
How to enrich your life and destroy doubt in five seconds. Throughout your life, you've had parents, coaches, teachers, friends, and mentors who have pushed you to be better than your excuses and bigger than your fears. What if the secret to having the confidence and courage to enrich your life and work is simply knowing how to push yourself?
-
-
I turned it off after an hour.
- By Zac on 04-08-17
By: Mel Robbins
-
Can't Hurt Me
- Master Your Mind and Defy the Odds
- By: David Goggins
- Narrated by: David Goggins, Adam Skolnick
- Length: 13 hrs and 37 mins
- Unabridged
-
Overall
-
Performance
-
Story
For David Goggins, childhood was a nightmare--poverty, prejudice, and physical abuse colored his days and haunted his nights. But through self-discipline, mental toughness, and hard work, Goggins transformed himself from a depressed, overweight young man with no future into a US Armed Forces icon and one of the world's top endurance athletes. The only man in history to complete elite training as a Navy SEAL, Army Ranger, and Air Force tactical air controller, he went on to set records in numerous endurance events.
-
-
Opting for the book instead
- By S David on 12-24-18
By: David Goggins
-
Take Control of Your Life
- How to Silence Fear and Win the Mental Game
- By: Mel Robbins
- Narrated by: Mel Robbins
- Length: 10 hrs and 3 mins
- Unabridged
-
Overall
-
Performance
-
Story
Mel Robbins is back! The international bestselling phenomenon and creator of The Five Second Rule and Kick Ass with Mel Robbins returns to help you tackle the single biggest obstacle you face: fear. This life-changing Audible Original features a powerful mix of one-on-one life-coaching sessions and a personal narrative with vital take-aways that you can start using immediately.
-
-
Stop living in fear
- By Nike7 on 02-08-19
By: Mel Robbins
-
The Art of War
- By: Sun Tzu
- Narrated by: Aidan Gillen
- Length: 1 hr and 7 mins
- Unabridged
-
Overall
-
Performance
-
Story
The 13 chapters of The Art of War, each devoted to one aspect of warfare, were compiled by the high-ranking Chinese military general, strategist, and philosopher Sun-Tzu. In spite of its battlefield specificity, The Art of War has found new life in the modern age, with leaders in fields as wide and far-reaching as world politics, human psychology, and corporate strategy finding valuable insight in its timeworn words.
-
-
The actual book The Art of War, not a commentary
- By Nemo71 on 12-31-19
By: Sun Tzu
-
F*ck Him!
- Nice Girls Always Finish Single
- By: Brian Keephimattracted, Brian Nox
- Narrated by: Jerod McBrayer
- Length: 2 hrs and 50 mins
- Unabridged
-
Overall
-
Performance
-
Story
The MANipulator manual. Keep your man interested and begging for more without playing games. So many women get in trouble in their love lives, and 99.9 percent of that trouble could have been avoided if they'd said "Well, f**k him!" a bit more often. Too many women are way too nice and compliant to their men, especially when these men don't deserve that kind of treatment. I, as a dating coach and author of books for women who want to get men, cannot take it anymore.
-
-
...
- By Emma R. on 02-01-18
By: Brian Keephimattracted, and others
-
The Let Them Theory
- A Life-Changing Tool That Millions of People Can’t Stop Talking About
- By: Mel Robbins
- Narrated by: Mel Robbins
- Length: 10 hrs and 38 mins
- Unabridged
-
Overall
-
Performance
-
Story
In her latest groundbreaking book, The Let Them Theory, Mel Robbins—New York Times bestselling author and one of the world's most respected experts on motivation, confidence, and mindset—teaches you how to stop wasting energy on what you can't control and start focusing on what truly matters: YOU. Your happiness. Your goals. Your life.
-
-
“…Grant me the serenity…”
- By Rachel Cornell on 12-25-24
By: Mel Robbins
-
The 5 Second Rule
- Transform your Life, Work, and Confidence with Everyday Courage
- By: Mel Robbins
- Narrated by: Mel Robbins
- Length: 7 hrs and 35 mins
- Unabridged
-
Overall
-
Performance
-
Story
How to enrich your life and destroy doubt in five seconds. Throughout your life, you've had parents, coaches, teachers, friends, and mentors who have pushed you to be better than your excuses and bigger than your fears. What if the secret to having the confidence and courage to enrich your life and work is simply knowing how to push yourself?
-
-
I turned it off after an hour.
- By Zac on 04-08-17
By: Mel Robbins
-
Can't Hurt Me
- Master Your Mind and Defy the Odds
- By: David Goggins
- Narrated by: David Goggins, Adam Skolnick
- Length: 13 hrs and 37 mins
- Unabridged
-
Overall
-
Performance
-
Story
For David Goggins, childhood was a nightmare--poverty, prejudice, and physical abuse colored his days and haunted his nights. But through self-discipline, mental toughness, and hard work, Goggins transformed himself from a depressed, overweight young man with no future into a US Armed Forces icon and one of the world's top endurance athletes. The only man in history to complete elite training as a Navy SEAL, Army Ranger, and Air Force tactical air controller, he went on to set records in numerous endurance events.
-
-
Opting for the book instead
- By S David on 12-24-18
By: David Goggins
-
Take Control of Your Life
- How to Silence Fear and Win the Mental Game
- By: Mel Robbins
- Narrated by: Mel Robbins
- Length: 10 hrs and 3 mins
- Unabridged
-
Overall
-
Performance
-
Story
Mel Robbins is back! The international bestselling phenomenon and creator of The Five Second Rule and Kick Ass with Mel Robbins returns to help you tackle the single biggest obstacle you face: fear. This life-changing Audible Original features a powerful mix of one-on-one life-coaching sessions and a personal narrative with vital take-aways that you can start using immediately.
-
-
Stop living in fear
- By Nike7 on 02-08-19
By: Mel Robbins
-
The Art of War
- By: Sun Tzu
- Narrated by: Aidan Gillen
- Length: 1 hr and 7 mins
- Unabridged
-
Overall
-
Performance
-
Story
The 13 chapters of The Art of War, each devoted to one aspect of warfare, were compiled by the high-ranking Chinese military general, strategist, and philosopher Sun-Tzu. In spite of its battlefield specificity, The Art of War has found new life in the modern age, with leaders in fields as wide and far-reaching as world politics, human psychology, and corporate strategy finding valuable insight in its timeworn words.
-
-
The actual book The Art of War, not a commentary
- By Nemo71 on 12-31-19
By: Sun Tzu
-
F*ck Him!
- Nice Girls Always Finish Single
- By: Brian Keephimattracted, Brian Nox
- Narrated by: Jerod McBrayer
- Length: 2 hrs and 50 mins
- Unabridged
-
Overall
-
Performance
-
Story
The MANipulator manual. Keep your man interested and begging for more without playing games. So many women get in trouble in their love lives, and 99.9 percent of that trouble could have been avoided if they'd said "Well, f**k him!" a bit more often. Too many women are way too nice and compliant to their men, especially when these men don't deserve that kind of treatment. I, as a dating coach and author of books for women who want to get men, cannot take it anymore.
-
-
...
- By Emma R. on 02-01-18
By: Brian Keephimattracted, and others
-
The 6 Habits of Growth
- By: Brendon Burchard
- Narrated by: Brendon Burchard
- Length: 5 hrs and 4 mins
- Original Recording
-
Overall
-
Performance
-
Story
The world’s leading high-performance coach and multiple New York Times best-selling author Brendon Burchard delivers the six habits of personal growth that will help you create the life of your dreams. Forged from Brendon Burchard’s personal experiences, data from his GrowthDay app, and his many years as a high-performance coach, The 6 Habits of Growth presents the tools you need to construct the life of your dreams.
-
-
Don’t bother
- By B. Sharpe on 10-30-22
By: Brendon Burchard
-
You Will Not Recognize Your Life
- By: Micaela Blei
- Narrated by: Micaela Blei
- Length: 2 hrs and 48 mins
- Original Recording
-
Overall
-
Performance
-
Story
It’s 2006. After a string of rejections from men who tell her they could never, ever, ever see her “that way,” awkward third-grade teacher Micaela Blei signs up for a mysterious course called “The Divine Feminine,” and feels like she might have found the key to the perfect life. Turns out if you’re an A student, you can get an A in anything–including men. Pretty soon she’s learning to "conjure" her desires with vision boards, flirtations, and even a daring jumbotron viewing party for her, ahem ... "divine center."
-
-
This is about real life.
- By Justin Ortgies on 12-14-24
By: Micaela Blei
-
The Daily Stoic
- 366 Meditations on Wisdom, Perseverance, and the Art of Living
- By: Ryan Holiday, Stephen Hanselman
- Narrated by: Brian Holsopple
- Length: 10 hrs and 6 mins
- Unabridged
-
Overall
-
Performance
-
Story
Why have history's greatest minds - from George Washington to Frederick the Great to Ralph Waldo Emerson along with today's top performers, from Super Bowl-winning football coaches to CEOs and celebrities - embraced the wisdom of the ancient Stoics? Because they realize that the most valuable wisdom is timeless and that philosophy is for living a better life, not a classroom exercise. The Daily Stoic offers a daily devotional of Stoic insights and exercises, featuring all-new translations.
-
-
Not well made as audio
- By Andreas on 12-27-16
By: Ryan Holiday, and others
-
12 Months to $1 Million
- How to Pick a Winning Product, Build a Real Business, and Become a Seven-Figure Entrepreneur
- By: Ryan Daniel Moran
- Narrated by: Ryan Daniel Moran
- Length: 7 hrs and 38 mins
- Unabridged
-
Overall
-
Performance
-
Story
By cutting out the noise and providing a clear and proven plan, this road map helps even brand-new entrepreneurs make decisions quickly, get their product up for sale, and launch it to a crowd that is ready and waiting to buy. This one-year plan will guide you through the three stages to your first $1 million: the Grind (months 0-4), the Growth (months 5-8), and the Gold (months 9-12). If your goal is to be a full-time entrepreneur, get ready for one chaotic, stressful, and rewarding year. If you have the guts to complete it, you will be the proud owner of a million-dollar business.
-
-
Good, but a Little Misleading
- By Chris Love on 11-28-20
-
Deep Sleep Hypnosis: Fall Asleep Instantly and Sleep Well
- By: Jasmine Harris
- Narrated by: Allison Mason
- Length: 2 hrs and 48 mins
- Unabridged
-
Overall
-
Performance
-
Story
A lack of quality sleep can hinder your alertness and quality of life while awake, as anyone with sleeping issues already knows. Suffering through sleepless nights does not have to be your reality. Instead you can fall asleep fast and get quality sleep tonight and every night. Hypnosis has been used for centuries to cure many ailments, including the inability to get better sleep. You can help yourself improve the quality of your life with hypnotherapy.
-
-
put me right to sleep
- By Cassandra on 05-08-17
By: Jasmine Harris
-
Self Help
- This Is Your Chance to Change Your Life
- By: Gabrielle Bernstein, Richard C. Schwartz - foreword
- Narrated by: Gabrielle Bernstein, Richard C. Schwartz - foreword
- Length: 6 hrs and 1 min
- Unabridged
-
Overall
-
Performance
-
Story
Are you ready to unlock the greatest resource of your life? Gabby Bernstein has written the ultimate self-help guide, offering a revolutionary practice to radically shift your core beliefs and connect you to an infallible inner guidance system: the energy of Self within you. In this groundbreaking book, Gabby demystifies the power of Internal Family Systems (IFS) Therapy, taking its life-changing teachings out of the therapist’s office and into your everyday life.
-
-
Self Serving
- By pricefreund on 01-14-25
By: Gabrielle Bernstein, and others