A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging.

Leading futurist and OneShared.World founder Jamie Metzl explores how genome sequencing, gene editing, artificial intelligence, and other technologies are not only changing our lives, but catalyzing each other in radical and accelerating ways. These technologies have the potential to improve our health, feed billions of people, supercharge our economies, and store essential information for millions of years, but can also—if we are not careful—do immeasurable harm.

In this remarkably clear and companionable audiobook, leading complex systems scientist Melanie Mitchell provides an intimate tour of the sciences of complexity, a broad set of efforts that seek to explain how large-scale complex, organized, and adaptive behavior can emerge from simple interactions among myriad individuals.

A scientist's exploration into the mysteries of the human mind. Neuroscience studies the brain, but what does science have to say about the mind? A full examination of what we mean by the term "mind" has traditionally been the province of philosophers, but what might neuroscience teach us about it? How does the mind differ from consciousness? And how do we know who we really are?

Astronomers have successfully observed a great deal of the universe’s history, from recording the afterglow of the big bang to imaging thousands of galaxies, and even to visualising an actual black hole. There’s a lot for astronomers to be smug about. But when it comes to understanding how the universe began and grew up, we are literally in the dark ages. In effect, we are missing the first one billion years from the timeline of the universe.

Since it was first published in 2005, Ray Kurzweil's The Singularity Is Near and its vision of the future have been influential in spawning a worldwide movement with millions of followers, hundreds of books, major films, and thousands of articles. During the succeeding decade, many of Kurzweil's predictions about technological advancements have been borne out, and their viability has become familiar to the public through such now commonplace concepts. In this entirely new book Ray Kurzweil brings a fresh perspective to advances in the singularity.

Humans have kept honey bees in hives for millennia, yet only in recent decades have biologists begun to investigate how these industrious insects live in the wild. The Lives of Bees is Thomas Seeley’s captivating story of what scientists are learning about the behavior, social life, and survival strategies of honey bees living outside the beekeeper’s hive - and how wild honey bees may hold the key to reversing the alarming die-off of the planet’s managed honey bee populations.

A new understanding of memory is emerging from the latest scientific research. In Why We Remember, pioneering neuroscientist and psychologist Charan Ranganath radically reframes the way we think about the everyday act of remembering. Combining accessible language with cutting-edge research, he reveals the surprising ways our brains record the past and how we use that information to understand who we are in the present, and to imagine and plan for the future.

Something new entered our world in November 2022—the first general purpose AI that could pass for a human and do the kinds of creative, innovative work that only humans could do previously. Wharton professor Ethan Mollick immediately understood what ChatGPT meant: after millions of years on our own, humans had developed a kind of co-intelligence that could augment, or even replace, human thinking. Through his writing, speaking, and teaching, Mollick has become one of the most prominent and provocative explainers of AI.

For the last 100,000 years, we Sapiens have accumulated enormous power. But despite all our discoveries, inventions, and conquests, we now find ourselves in an existential crisis. The world is on the verge of ecological collapse. Misinformation abounds. And we are rushing headlong into the age of AI—a new information network that threatens to annihilate us. For all that we have accomplished, why are we so self-destructive? Nexus looks through the long lens of human history to consider how the flow of information has shaped us, and our world.

How does a neural network become a brain? While neurobiologists investigate how nature accomplishes this feat, computer scientists interested in AI strive to achieve this through technology. The Self-Assembling Brain tells the stories of both fields, exploring the historical and modern approaches taken by the scientists pursuing answers to the quandary: What information is necessary to make an intelligent neural network? As Peter Robin Hiesinger argues, "the information problem" underlies both fields.

Our understanding of cancer is slowly undergoing a revolution, allowing for the development of more effective treatments. For the first time ever, the death rate from cancer is showing a steady decline...but the “War on Cancer” has hardly been won. In The Cancer Code, Dr. Jason Fung offers a revolutionary new understanding of this invasive, often fatal disease - what it is, how it manifests, and why it is so challenging to treat.

By the star physicist and author of multiple #1 Sunday Times bestsellers, a major and definitive narrative work on black holes and how they can help us understand the universe.

Equal parts Sapiens, Behave, and Superintelligence, but wholly original in scope, A Brief History of Intelligence offers a paradigm shift for how we understand neuroscience and AI. Artificial intelligence entrepreneur Max Bennett chronicles the five “breakthroughs” in the evolution of human intelligence and reveals what brains of the past can tell us about the AI of tomorrow.

My Big TOE: Awakening, written by a nuclear physicist in the language of contemporary culture, unifies science and philosophy, physics and metaphysics, mind and matter, purpose and meaning, the normal and the paranormal. The entirety of human experience (mind, body, and spirit) including both our objective and subjective worlds is brought together under one seamless scientific understanding.

Chemistry and Our Universe: How It All Works is your in-depth introduction to this vital field, taught through 60 engaging half-hour lectures that are suitable for any background or none at all. Covering a year’s worth of introductory general chemistry at the college level, plus intriguing topics that are rarely discussed in the classroom, this amazingly comprehensive course requires nothing more advanced than high-school math. Your guide is Professor Ron B. Davis, Jr., a research chemist and award-winning teacher at Georgetown University.

Richard Dawkins' brilliant reformulation of the theory of natural selection has the rare distinction of having provoked as much excitement and interest outside the scientific community as within it. His theories have helped change the whole nature of the study of social biology, and have forced thousands to rethink their beliefs about life.

How the Earth Works takes you on an astonishing journey through time and space. In 48 lectures, you will look at what went into making our planet - from the big bang, to the formation of the solar system, to the subsequent evolution of Earth.

We are in the midst of a global mental health crisis, and mental illnesses are on the rise. But what causes mental illness? And why are mental health problems so hard to treat? Drawing on decades of research, Harvard psychiatrist Dr. Chris Palmer outlines a revolutionary new understanding that for the first time unites our existing knowledge about mental illness within a single framework: mental disorders are metabolic disorders of the brain. Brain Energy will transform the field of mental health, and the lives of countless people around the world.

Astrophysicist Neil deGrasse Tyson has attracted one of the world’s largest online followings with his fascinating, widely accessible insights into science and our universe. Now, Tyson invites us to go behind the scenes of his public fame by unveiling his candid correspondence with people across the globe who have sought him out in search of answers. In this hand-picked collection of 100 letters, Tyson draws upon cosmic perspectives to address a vast array of questions about science, faith, philosophy, life, and of course, Pluto.

Hilarious, fascinating, and a roller coaster of dizzying, historical what-ifs, Napoleon's Hemorrhoids is a potpourri for serious historians and casual history buffs. In one of Phil Mason's many revelations, you'll learn that Communist jets were two minutes away from opening fire on American planes during the Cuban missile crisis, when they had to turn back as they were running out of fuel. You'll discover that before the Battle of Waterloo, Napoleon's painful hemorrhoids prevented him from mounting his horse to survey the battlefield.

Dr. Catherine Kleier invites us to open our eyes to the phenomenal world of plant life and to the process she calls “Natura Revelata”, the joy of celebrating and learning from the secrets of nature. As Dr. Kleier shares her knowledge with contagious excitement for her subject, she emphasizes the middle ground: Instead of focusing on cell microbiology or the study of ecosystems and habitats, she stresses the basic biology, function, and the amazing adaptations of the plants we see all around us.

In this illuminating audiobook, Tyson and coauthor James Trefil, a renowned physicist and science popularizer, take on the big questions that humanity has been posing for millennia - How did life begin? What is our place in the universe? Are we alone? - and provide answers based on the most current data, observations, and theories.

At the end of his career, Albert Einstein was pursuing a dream far more ambitious than the theory of relativity. He was trying to find an equation that explained all physical reality - a theory of everything. Experimental physicist and award-winning educator Dr. Don Lincoln takes you on this exciting journey in The Theory of Everything: The Quest to Explain All Reality. Suitable for the intellectually curious at all levels and assuming no background beyond basic high-school math, these 24 half-hour lectures cover recent developments at the forefront of particle physics and cosmology.

Of all the things humans rely on plants for - sustenance, beauty, medicine, fragrance, flavor, fiber - surely the most curious is our use of them to change consciousness: to stimulate or calm, fiddle with or completely alter, the qualities of our mental experience. Take coffee and tea: People around the world rely on caffeine to sharpen their minds. But we do not usually think of caffeine as a drug, or our daily use as an addiction, because it is legal and socially acceptable.

A scientist's exploration into the mysteries of the human mind. Neuroscience studies the brain, but what does science have to say about the mind? A full examination of what we mean by the term "mind" has traditionally been the province of philosophers, but what might neuroscience teach us about it? How does the mind differ from consciousness? And how do we know who we really are?

This urgent and eye-opening book makes the case that protecting humanity's future is the central challenge of our time. If all goes well, human history is just beginning. Our species could survive for billions of years - enough time to end disease, poverty, and injustice, and to flourish in ways unimaginable today. But this vast future is at risk. With the advent of nuclear weapons, humanity entered a new age, where we face existential catastrophes - those from which we could never come back.

Our understanding of cancer is slowly undergoing a revolution, allowing for the development of more effective treatments. For the first time ever, the death rate from cancer is showing a steady decline...but the “War on Cancer” has hardly been won. In The Cancer Code, Dr. Jason Fung offers a revolutionary new understanding of this invasive, often fatal disease - what it is, how it manifests, and why it is so challenging to treat.

Your body is incredible, but it’s also out to destroy you. Your brain is like an early computer operating system, riddled with bad code, slow to load, and more likely to watch cat memes than go to sleep. You’d be a mess without your skeleton, but it can be a bony cage if you’re tortured by backaches, niggling neck pain, and knee joints that crumble under pressure. And your nose is a design disaster, getting blocked, springing leaks, and growing random tufts of hair.

By the star physicist and author of multiple #1 Sunday Times bestsellers, a major and definitive narrative work on black holes and how they can help us understand the universe.

Villains of All Nations explores the "Golden Age" of Atlantic piracy (1716-1726) and the infamous generation whose images underlie our modern, romanticized view of pirates.

We are living through the most prosperous age in all of human history, yet we are listless, divided, and miserable. Wealth and comfort are unparalleled, but our political landscape is unmoored, and rates of suicide, lone­liness, and chronic illness continue to skyrocket. How do we explain the gap between these truths? And how should we respond? For evolutionary biologists Heather Heying and Bret Weinstein, the cause of our troubles is clear: The accelerat­ing rate of change in the modern world has outstripped the capacity of our brains and bodies to adapt.

Are you up for a trip through the ultimate neighborhood? Join astrophysicist Hugh Ross for an insider’s look at our cosmic neighborhood, where you’ll see everything from the largest-scale structure of the universe to Earth’s innermost layers. In Designed to the Core, Ross explains how the most sophisticated scientific instruments reveal exquisite “interior designs” throughout the universe that are ideally suited for human habitation here on Earth right now.

Ever since its first publication in 1992, The End of History and the Last Man has provoked controversy and debate. Francis Fukuyama's prescient analysis of religious fundamentalism, politics, scientific progress, ethical codes, and war is as essential for a world fighting fundamentalist terrorists as it was for the end of the Cold War. Now updated with a new afterword, The End of History and the Last Man is a modern classic.

What is art? Many of us think of the arts as entertainment—a luxury of some kind. In Your Brain on Art, authors Susan Magsamen and Ivy Ross show how activities from painting and dancing to expressive writing, architecture, and more are essential to our lives.

Smart people are not only just as prone to making mistakes as everyone else - they may be even more susceptible to them. This is the "intelligence trap", the subject of David Robson's fascinating and provocative book. The Intelligence Trap explores cutting-edge ideas in our understanding of intelligence and expertise, including "strategic ignorance", "meta-forgetfulness", and "functional stupidity."

As seekers and practitioners reclaim and restore magic to its rightful place among powerful forces for social, personal, and political transformation, more people than ever are claiming the identity of "witch". But our knowledge of witchcraft and magic has been marred by erasure, sensationalism, and sterilization, the true stories of history's witches left untold. Through meditations, stories, and practices, authors Risa Dickens and Amy Torok offer an intersectional, contemporary lens for uncovering and reconnecting with feminist witch history.

They live in shadows - deep in the forest, late in the night, in the dark recesses of our minds. They're spoken of in stories and superstitions, relics of an unenlightened age, old wives' tales, passed down through generations. Yet no matter how wary and jaded we have become, as individuals or as a society, a part of us remains vulnerable to them: werewolves and wendigos, poltergeists and vampires, angry elves and vengeful spirits.

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.