Elusive Cures sheds light on one of the most daunting challenges confronted by science while offering hope for revolutionary new treatments and cures for the brain.

The renowned biologist Paul Nurse has spent his career revealing how living cells work. In What Is Life?, he takes up the challenge of describing what it means to be alive in a way that every listener can understand. It is a shared journey of discovery; step-by-step Nurse illuminates five great ideas that underpin biology - the Cell, the Gene, Evolution by Natural Selection, Life as Chemistry, and Life as Information.

What is life? This is among the most difficult open problems in science, right up there with the nature of consciousness and the existence of matter. All the definitions we have fall short. None help us understand how life originates or the full range of possibilities for what life on other planets might look like. In Life as No One Knows It, physicist and astrobiologist Sara Imari Walker argues that solving the origin of life requires radical new thinking and an experimentally testable theory for what life is.

From a rare and deadly amniotic avalanche to a victim of roasted peanuts ... The bestselling author of The Cause of Death and The Quick and the Dead returns with more stranger-than-fiction stories of death, disease and murder—as well as new perspectives on high-profile cases, including the disappearance of Ben Smart and Olivia Hope, the trial of Mark Lundy, and the ill-fated journey of Ansett Flight 703.

Leading futurist and OneShared.World founder Jamie Metzl explores how genome sequencing, gene editing, artificial intelligence, and other technologies are not only changing our lives, but catalyzing each other in radical and accelerating ways. These technologies have the potential to improve our health, feed billions of people, supercharge our economies, and store essential information for millions of years, but can also—if we are not careful—do immeasurable harm.

2020 saw a spike in deaths in America, smaller than you might imagine during a pandemic, some of which could be attributed to COVID and to initial treatment strategies that were not effective. But then, in 2021, the stats people expected went off the rails. The CEO of the OneAmerica insurance company publicly disclosed that during the third and fourth quarters of 2021, death in people of working age (18–64) was 40 percent higher than it was before the pandemic. Significantly, the majority of the deaths were not attributed to COVID.

Food. There's plenty of it around, and we all love to eat it. So why should anyone need to defend it? Because in the so-called Western diet, food has been replaced by nutrients, and common sense by confusion—most of what we’re consuming today is longer the product of nature but of food science. The result is what Michael Pollan calls the American Paradox: The more we worry about nutrition, the less healthy we see to become.

Dr. Topol’s unprecedented, evidenced-based guide is about how you and your family and friends can benefit from new treatments coming available at a faster rate than ever. From his unique position as a leader overseeing millions in research funding, Dr. Topol also explains the fundamental reasons—from semaglutides to AI—that we can be confident these breakthroughs will continue. Ninety-five percent of Americans over sixty have at least one chronic disease and almost as many have two. That is the essential problem this revolution is solving.

Throughout history, technological change — whether it takes the form of agricultural improvements in the Middle Ages, the Industrial Revolution, or today’s artificial intelligence — has been viewed as a main driver of prosperity, working in the public interest. The reality, though, is that technology is shaped by what powerful people want and believe, generating riches, social respect, cultural prominence, and further political voice for those already powerful. For most of the rest of us, there is the illusion of progress.

In 1961, the University of Chicago Press published Richmond Lattimore's translation of Homer’s The Iliad. For more than sixty years, it has served to introduce readers to the ancient Greek world of gods and heroes and has been one of the most popular and respected versions of the work. Yet through all those decades, Chicago never published a companion translation of the best-known epic in the Western canon, The Odyssey—until now.

Brimming with fascinating historical details and modern medical wonders, this important audiobook is a fascinating glimpse into the struggles and "eureka!" moments that people outside of the medical profession rarely see. Written with Dr. Mukherjee's signature eloquence and passionate prose, The Laws of Medicine is a critical book not just for those in the medical profession but for everyone who is moved to better understand how their health and well-being are being treated.

Can space be divided into smaller and smaller units, ad infinitum? Does space extend to larger and larger regions, on and on to infinity? Is consciousness reducible to the material brain and its neurons? What was the origin of life, and can biologists create life from scratch in the lab? Physicist and novelist Alan Lightman explores these questions and more - from the anatomy of a smile to the capriciousness of memory to the specialness of life in the universe to what came before the Big Bang.

In Blind Spots, Dr. Makary explores the latest research on critical topics ranging from the microbiome to childbirth to nutrition and longevity and more, revealing the biggest blind spots of modern medicine and tackling the most urgent yet unsung issues in our $4.5 trillion health care ecosystem. The path to medical mishaps can be absurd, entertaining, and jaw-dropping—but the truth is essential to our health.

Since it was first published in 2005, Ray Kurzweil's The Singularity Is Near and its vision of the future have been influential in spawning a worldwide movement with millions of followers, hundreds of books, major films, and thousands of articles. During the succeeding decade, many of Kurzweil's predictions about technological advancements have been borne out, and their viability has become familiar to the public through such now commonplace concepts. In this entirely new book Ray Kurzweil brings a fresh perspective to advances in the singularity.

The form and function of a sprinting cheetah are quite unlike those of a rooted tree. A human being is very different from a bacterium or a zebra. The living world is a realm of dazzling variety, yet a shared set of physical principles shapes the forms and behaviors of every creature in it. So Simple a Beginning shows how the emerging new science of biophysics is transforming our understanding of life on Earth and enabling potentially lifesaving but controversial technologies such as gene editing, artificial organ growth, and ecosystem engineering.

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.

Have you wondered why some 60-year-olds look and feel like 40-year-olds and why some 40-year-olds look and feel like 60-year-olds? While many factors contribute to aging and illness, Dr. Elizabeth Blackburn discovered a biological indicator called telomerase, the enzyme that replenishes telomeres, which protect our genetic heritage. Dr. Blackburn and Dr. Elissa Epel's research shows that the length and health of one's telomeres are a biological underpinning of the long-hypothesized mind-body connection.

From an acclaimed Harvard professor and one of Time’s most influential people, this paradigm-shifting audiobook shows how almost everything we think we know about aging is wrong, offers a front-row seat to the amazing global effort to slow, stop, and reverse aging, and calls listeners to consider a future where aging can be treated.

All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging.

Whether it’s the mighty pyramids of Egypt or the majestic temples of Mexico, we have a good idea of what the past looked like. But what about our other senses: The tang of Roman fish sauce and the springy crust of Egyptian sourdough? The boom of medieval cannons and the clash of Viking swords? The frenzied plays of an Aztec ballgame...and the chilling reality that the losers might also lose their lives?

The great auk is one of the most tragic and documented examples of extinction. A flightless bird that bred primarily on the remote islands of the North Atlantic, the last of its kind were killed in Iceland in 1844. Gisli Pálsson draws on firsthand accounts from the Icelanders who hunted the last great auks to bring to life a bygone age of Victorian scientific exploration while offering vital insights into the extinction of species.

Aging - not cancer, not heart disease - is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: There are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are.

What should we eat? It's a simple and fundamental question that still bewilders us despite a seemingly infinite amount of available information on which foods are best for our bodies. Scientists, dieticians, and even governments regularly publish research on the dangers of too much fat and sugar as well as on the benefits of exercise, and yet the global obesity crisis is only worsening. Most diet plans prove to be only short-term solutions, and few strategies work for everyone.

At its simplest, Bayes’s theorem describes the probability of an event, based on prior knowledge of conditions that might be related to the event. But in Everything Is Predictable, Tom Chivers lays out how it affects every aspect of our lives. He explains why highly accurate screening tests can lead to false positives and how a failure to account for it in court has put innocent people in jail. A cornerstone of rational thought, many argue that Bayes’s theorem is a description of almost everything. But who was the man who lent his name to this theorem?

When Zoë Boehm agrees to track down the gang who knocked over Sweeney’s jewellery shop, she certainly doesn’t expect to wind up in a coffin. But she’s about to become entangled with a strange collection of characters, starting with suicidal Tim Whitby, who’s dedicating what’s left of his life to protecting Katrina Blake from her late husband’s brothers, Arkle and Trent. Unfortunately for Zoë, Arkle has a crossbow, Tim has nothing left to lose and even Katrina has her secrets.

A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

Why do women live longer than men? Why do women have menopause? Why are women more likely to get Alzheimer’s? Why do girls score better at every academic subject than boys until puberty, when suddenly their scores plummet? And does the female brain really exist? In Eve, Cat Bohannon answers questions scientists should have been addressing for decades. With boundless curiosity and sharp wit, she covers the past 200 million years to explain the specific science behind the development of the female sex.

The most trusted explainer of the most mind-boggling concepts pulls back the veil of mystery that has too long cloaked the most valuable building blocks of modern science. Sean Carroll, with his genius for making complex notions entertaining, presents in his uniquely lucid voice the fundamental ideas informing the modern physics of reality. In the tradition of the legendary Richard Feynman lectures presented sixty years ago, this book is an inspiring, dazzling introduction to a way of seeing that will resonate across cultural and generational boundaries for many years to come.

Nate Silver built an innovative system for predicting baseball performance, predicted the 2008 election within a hair’s breadth, and became a national sensation as a blogger - all by the time he was 30. He solidified his standing as the nation's foremost political forecaster with his near perfect prediction of the 2012 election. Silver is the founder and editor in chief of the website FiveThirtyEight. Drawing on his own groundbreaking work, Silver examines the world of prediction, investigating how we can distinguish a true signal from a universe of noisy data.

How would you like to know what the people around you are thinking? Would you like to network like a pro, persuade your boss to give you that promotion, and finally become the life of every party? Now, with Henrik Fexeus' expertise, you can. This international best seller teaches you everything you need to know in order to become an expert at mind-reading.