Leading futurist and OneShared.World founder Jamie Metzl explores how genome sequencing, gene editing, artificial intelligence, and other technologies are not only changing our lives, but catalyzing each other in radical and accelerating ways. These technologies have the potential to improve our health, feed billions of people, supercharge our economies, and store essential information for millions of years, but can also—if we are not careful—do immeasurable harm.

The renowned biologist Paul Nurse has spent his career revealing how living cells work. In What Is Life?, he takes up the challenge of describing what it means to be alive in a way that every listener can understand. It is a shared journey of discovery; step-by-step Nurse illuminates five great ideas that underpin biology - the Cell, the Gene, Evolution by Natural Selection, Life as Chemistry, and Life as Information.

All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging.

In Waves in an Impossible Sea, physicist Matt Strassler tells a startling tale of elementary particles, human experience, and empty space. He begins with a simple mystery of motion. When we drive at highway speeds with the windows down, the wind beats against our faces. Yet our planet hurtles through the cosmos at 150 miles per second, and we feel nothing of it. How can our voyage be so tranquil when, as Einstein discovered, matter warps space, and space deflects matter? The answer, Strassler reveals, is that empty space is a sea, albeit a paradoxically strange one.

A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

In Then I Am Myself the World, Christof Koch explores the only thing we directly experience: consciousness. At the book's heart is integrated-information theory, the idea that the essence of consciousness is the ability to exert causal power over itself, to be an agent of change. Koch investigates the physical origins of consciousness in the brain and how this knowledge can be used to measure consciousness in natural and artificial systems.

Explore the world through its most unlikely creatures: Cryptozoology, the study of hidden, monstrous, and legendary animals, is truly the art of discovering the unknown. Richard Freeman, Zoological Director of Centre for Fortean Zoology, has explored the corners of the five continents on the search for creatures that many people believe are non-existent. In this book, he shares the exciting stories of his investigations of the Yeti, Mongolian Deathworm, Loch Ness Monster, Orang-Pendak, Ninki-Naka, and more.

Vince Beiser explores the Achilles’ heel of “green power” and digital technology–that manufacturing computers, cell phones, electric cars, and other technologies demand skyrocketing amounts of lithium, copper, cobalt, and other materials. Around the world, businesses and governments are scrambling for new places and new ways to get those metals, at enormous cost to people and the planet. Beiser crisscrossed the world to talk to the people involved and report on the damage this race is inflicting, the ways it could get worse, and how we can minimize the damage.

Food. There's plenty of it around, and we all love to eat it. So why should anyone need to defend it? Because in the so-called Western diet, food has been replaced by nutrients, and common sense by confusion—most of what we’re consuming today is longer the product of nature but of food science. The result is what Michael Pollan calls the American Paradox: The more we worry about nutrition, the less healthy we see to become.

In this landmark book of popular science, Daniel E. Lieberman - chair of the department of human evolutionary biology at Harvard University and a leader in the field - gives us a lucid and engaging account of how the human body evolved over millions of years, even as it shows how the increasing disparity between the jumble of adaptations in our Stone Age bodies and advancements in the modern world is occasioning this paradox: greater longevity but increased chronic disease.

Three of the most important words in science are I don't know. Not knowing implies a universe of opportunities—the possibility of discovery and surprise. Our understanding of science has advanced immeasurably over the last 500 years, yet many fundamental mysteries of existence persist: How did our universe begin? How big is the universe? Is time travel possible? What’s at the center of a black hole? How did life on Earth arise? Are we alone? What is consciousness, and can we create it?

We are living through a revolution in machine learning-powered AI that shows no signs of slowing down. This technology is based on relatively simple mathematical ideas, some of which go back centuries, including linear algebra and calculus, the stuff of seventeenth- and eighteenth-century mathematics. It took the birth and advancement of computer science and the kindling of 1990s computer chips designed for video games to ignite the explosion of AI that we see today. In this enlightening book, Anil Ananthaswamy explains the fundamental math behind machine learning.

What is life? This is among the most difficult open problems in science, right up there with the nature of consciousness and the existence of matter. All the definitions we have fall short. None help us understand how life originates or the full range of possibilities for what life on other planets might look like. In Life as No One Knows It, physicist and astrobiologist Sara Imari Walker argues that solving the origin of life requires radical new thinking and an experimentally testable theory for what life is.

Since it was first published in 2005, Ray Kurzweil's The Singularity Is Near and its vision of the future have been influential in spawning a worldwide movement with millions of followers, hundreds of books, major films, and thousands of articles. During the succeeding decade, many of Kurzweil's predictions about technological advancements have been borne out, and their viability has become familiar to the public through such now commonplace concepts. In this entirely new book Ray Kurzweil brings a fresh perspective to advances in the singularity.

A tiny mutation on the X chromosome can shape a family’s history. Passed down from a “carrier” parent to a child, fragile X syndrome is the most common inherited cause of intellectual disability and autism. Beyond that—and a rarity among genetic disorders—some fragile X carriers not only transmit the mutation, but also experience related conditions themselves.

We are in the midst of a global mental health crisis, and mental illnesses are on the rise. But what causes mental illness? And why are mental health problems so hard to treat? Drawing on decades of research, Harvard psychiatrist Dr. Chris Palmer outlines a revolutionary new understanding that for the first time unites our existing knowledge about mental illness within a single framework: mental disorders are metabolic disorders of the brain. Brain Energy will transform the field of mental health, and the lives of countless people around the world.

My Big TOE: Awakening, written by a nuclear physicist in the language of contemporary culture, unifies science and philosophy, physics and metaphysics, mind and matter, purpose and meaning, the normal and the paranormal. The entirety of human experience (mind, body, and spirit) including both our objective and subjective worlds is brought together under one seamless scientific understanding.

How the Earth Works takes you on an astonishing journey through time and space. In 48 lectures, you will look at what went into making our planet - from the big bang, to the formation of the solar system, to the subsequent evolution of Earth.

Richard Dawkins' brilliant reformulation of the theory of natural selection has the rare distinction of having provoked as much excitement and interest outside the scientific community as within it. His theories have helped change the whole nature of the study of social biology, and have forced thousands to rethink their beliefs about life.

Hilarious, fascinating, and a roller coaster of dizzying, historical what-ifs, Napoleon's Hemorrhoids is a potpourri for serious historians and casual history buffs. In one of Phil Mason's many revelations, you'll learn that Communist jets were two minutes away from opening fire on American planes during the Cuban missile crisis, when they had to turn back as they were running out of fuel. You'll discover that before the Battle of Waterloo, Napoleon's painful hemorrhoids prevented him from mounting his horse to survey the battlefield.

How do today's most successful tech companies - Amazon, Google, Facebook, Netflix, Tesla - design, develop, and deploy the products that have earned the love of literally billions of people around the world? Perhaps surprisingly, they do it very differently from the vast majority of tech companies. In Inspired, technology product management thought leader Marty Cagan provides listeners with a master class in how to structure and staff a vibrant and successful product organization and how to discover and deliver technology products that your customers will love.

Astrophysicist Neil deGrasse Tyson has attracted one of the world’s largest online followings with his fascinating, widely accessible insights into science and our universe. Now, Tyson invites us to go behind the scenes of his public fame by unveiling his candid correspondence with people across the globe who have sought him out in search of answers. In this hand-picked collection of 100 letters, Tyson draws upon cosmic perspectives to address a vast array of questions about science, faith, philosophy, life, and of course, Pluto.

Welcome to the Universe is a personal guided tour of the cosmos by three of today's leading astrophysicists. Inspired by the enormously popular introductory astronomy course that Neil deGrasse Tyson, Michael A. Strauss, and J. Richard Gott taught together at Princeton, this book covers it all - from planets, stars, and galaxies to black holes, wormholes, and time travel.

The real stories behind the scenery of America’s national parks. For 12 years, Andrea Lankford lived in the biggest, most impressive national parks in the world, working a job she loved. She chaperoned baby sea turtles on their journey to sea. She pursued bad guys on her galloping patrol horse. She jumped into rescue helicopters bound for the heart of the Grand Canyon. She won arguments with bears. She slept with a few too many rattlesnakes. Hell yeah, it was the best job in the world! Fortunately, Andrea survived it.

In The Quantum Universe, Brian Cox and Jeff Forshaw approach the world of quantum mechanics in the same way they did in Why Does E=mc2? and make fundamental scientific principles accessible - and fascinating - to everyone.The subatomic realm has a reputation for weirdness, spawning any number of profound misunderstandings, journeys into Eastern mysticism, and woolly pronouncements on the interconnectedness of all things. Cox and Forshaw's contention? There is no need for quantum mechanics to be viewed this way.

All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging.

Everyone has heard of DNA. But by itself, DNA is just an inert blueprint for life. It is the ribosome - an enormous molecular machine made up of a million atoms - that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases.

A scientist's exploration into the mysteries of the human mind. Neuroscience studies the brain, but what does science have to say about the mind? A full examination of what we mean by the term "mind" has traditionally been the province of philosophers, but what might neuroscience teach us about it? How does the mind differ from consciousness? And how do we know who we really are?

A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

Riveting and timely, a look at the research that is transforming our understanding of the cosmos in the quest to discover whether we are alone.

From an acclaimed Harvard professor and one of Time’s most influential people, this paradigm-shifting audiobook shows how almost everything we think we know about aging is wrong, offers a front-row seat to the amazing global effort to slow, stop, and reverse aging, and calls listeners to consider a future where aging can be treated.

Aging - not cancer, not heart disease - is the underlying cause of most human death and suffering. The same cascade of biological changes that renders us wrinkled and gray also opens the door to dementia and disease. We work furiously to conquer each individual disease, but we never think to ask: Is aging itself necessary? Nature tells us it is not: There are tortoises and salamanders who are spry into old age and whose risk of dying is the same no matter how old they are.

Through engaging storytelling, human behavior insights, and proven design techniques, Kevin Kelley—an attention architect and cofounder of Shook Kelley, a strategic design firm that pioneered the field of "convening"—unfolds why physical places are essential to civil society, business, and community.

Become body literate with Heart: An Owner's Guide, the next book in The Body Literacy Library, an enlightening series that will democratize health for a new generation of listeners. Heart: An Owner's Guide is an informative, practical, and engaging introduction to all aspects of heart health with the goal of living well and longer. Find out what is the key to a long, healthy life, and what is your own personal cardiac risk.

Breakthroughs in cutting-edge longevity, regenerative, and performance, science and technology are making it possible to experience vitality, resilience, and the joy of youthfulness for the duration of your lifetime. We have grown up in a culture that has normalized aging. For generations, we have dreaded and feared growing older and losing our abilities and independence but we saw no other option.

Recent advances in medicine and technology have expanded our understanding of aging across the animal kingdom, and our own timeless quest for the fountain of youth. Yet, despite modern humans living longer today than ever before, the public’s understanding of what is possible is limited to our species—until now. In this spunky, effervescent debut, the key to immortality is revealed to be a superpower within reach.

When and how did the universe begin? Why are we here? What is the nature of reality? Is the apparent “grand design” of our universe evidence of a benevolent creator who set things in motion—or does science offer another explanation? In The Grand Design, Stephen Hawking and Leonard Mlodinow present the most illuminating scientific thinking about these and other abiding mysteries of the universe, in nontechnical language marked by brilliance and simplicity.

From the author of The Emperor of All Maladies, winner of the Pulitzer Prize, and The Gene, a #1 New York Times bestseller, comes his most spectacular book yet, an exploration of medicine and our radical new ability to manipulate cells. Rich with Mukherjee’s revelatory and exhilarating stories of scientists, doctors, and the patients whose lives may be saved by their work, The Song of the Cell is the third book in this extraordinary writer’s exploration of what it means to be human.

Our lives are filled with repetitive tasks meant to keep us on track—what we come to know as habits. Over time, these routines (like brushing your teeth or putting on your right sock first) tend to be performed automatically. But when we’re more mindful about these actions—when we focus on the precise way they are performed—they can instead become rituals. Shifting from a “habitual” mindset to a “ritual” mindset can convert ordinary acts from black and white to technicolor.

Every day we draw in two thousand gallons of air—and thousands of living things. From the ground to the stratosphere, the air teems with invisible life. This last great biological frontier remains so mysterious that it took over two years for scientists to finally agree that the COVID pandemic was caused by an airborne virus. In Air-Borne, award-winning New York Times columnist and author Carl Zimmer leads us on an odyssey through the living atmosphere and through the history of its discovery.