A gripping journey of discovery, The Catalyst moves from the early experiments that first hinted at RNA's spectacular powers, to Cech's own paradigm-shifting finding that it can catalyze cellular reactions, to the cutting-edge biotechnologies poised to reshape our health.

A scientist's exploration into the mysteries of the human mind. Neuroscience studies the brain, but what does science have to say about the mind? A full examination of what we mean by the term "mind" has traditionally been the province of philosophers, but what might neuroscience teach us about it? How does the mind differ from consciousness? And how do we know who we really are?

By the star physicist and author of multiple #1 Sunday Times bestsellers, a major and definitive narrative work on black holes and how they can help us understand the universe.

The renowned biologist Paul Nurse has spent his career revealing how living cells work. In What Is Life?, he takes up the challenge of describing what it means to be alive in a way that every listener can understand. It is a shared journey of discovery; step-by-step Nurse illuminates five great ideas that underpin biology - the Cell, the Gene, Evolution by Natural Selection, Life as Chemistry, and Life as Information.

Humans have kept honey bees in hives for millennia, yet only in recent decades have biologists begun to investigate how these industrious insects live in the wild. The Lives of Bees is Thomas Seeley’s captivating story of what scientists are learning about the behavior, social life, and survival strategies of honey bees living outside the beekeeper’s hive - and how wild honey bees may hold the key to reversing the alarming die-off of the planet’s managed honey bee populations.

We are living through a revolution in machine learning-powered AI that shows no signs of slowing down. This technology is based on relatively simple mathematical ideas, some of which go back centuries, including linear algebra and calculus, the stuff of seventeenth- and eighteenth-century mathematics. It took the birth and advancement of computer science and the kindling of 1990s computer chips designed for video games to ignite the explosion of AI that we see today. In this enlightening book, Anil Ananthaswamy explains the fundamental math behind machine learning.

Our understanding of cancer is slowly undergoing a revolution, allowing for the development of more effective treatments. For the first time ever, the death rate from cancer is showing a steady decline...but the “War on Cancer” has hardly been won. In The Cancer Code, Dr. Jason Fung offers a revolutionary new understanding of this invasive, often fatal disease - what it is, how it manifests, and why it is so challenging to treat.

In Then I Am Myself the World, Christof Koch explores the only thing we directly experience: consciousness. At the book's heart is integrated-information theory, the idea that the essence of consciousness is the ability to exert causal power over itself, to be an agent of change. Koch investigates the physical origins of consciousness in the brain and how this knowledge can be used to measure consciousness in natural and artificial systems.

In this remarkably clear and companionable audiobook, leading complex systems scientist Melanie Mitchell provides an intimate tour of the sciences of complexity, a broad set of efforts that seek to explain how large-scale complex, organized, and adaptive behavior can emerge from simple interactions among myriad individuals.

Of all the things humans rely on plants for - sustenance, beauty, medicine, fragrance, flavor, fiber - surely the most curious is our use of them to change consciousness: to stimulate or calm, fiddle with or completely alter, the qualities of our mental experience. Take coffee and tea: People around the world rely on caffeine to sharpen their minds. But we do not usually think of caffeine as a drug, or our daily use as an addiction, because it is legal and socially acceptable.

All of us would like to live longer, or to slow the debilitating effects of age. In How We Age, Coleen Murphy shows how recent research on longevity and aging may be bringing us closer to this goal. Murphy, a leading scholar of aging, explains that the study of model systems, particularly simple invertebrate animals, combined with breakthroughs in genomic methods, have allowed scientists to probe the molecular mechanisms of longevity and aging.

Something new entered our world in November 2022—the first general purpose AI that could pass for a human and do the kinds of creative, innovative work that only humans could do previously. Wharton professor Ethan Mollick immediately understood what ChatGPT meant: after millions of years on our own, humans had developed a kind of co-intelligence that could augment, or even replace, human thinking. Through his writing, speaking, and teaching, Mollick has become one of the most prominent and provocative explainers of AI.

What is life? This is among the most difficult open problems in science, right up there with the nature of consciousness and the existence of matter. All the definitions we have fall short. None help us understand how life originates or the full range of possibilities for what life on other planets might look like. In Life as No One Knows It, physicist and astrobiologist Sara Imari Walker argues that solving the origin of life requires radical new thinking and an experimentally testable theory for what life is.

How would you like to know what the people around you are thinking? Would you like to network like a pro, persuade your boss to give you that promotion, and finally become the life of every party? Now, with Henrik Fexeus' expertise, you can. This international best seller teaches you everything you need to know in order to become an expert at mind-reading.

What is art? Many of us think of the arts as entertainment—a luxury of some kind. In Your Brain on Art, authors Susan Magsamen and Ivy Ross show how activities from painting and dancing to expressive writing, architecture, and more are essential to our lives.

How the Earth Works takes you on an astonishing journey through time and space. In 48 lectures, you will look at what went into making our planet - from the big bang, to the formation of the solar system, to the subsequent evolution of Earth.

Chemistry and Our Universe: How It All Works is your in-depth introduction to this vital field, taught through 60 engaging half-hour lectures that are suitable for any background or none at all. Covering a year’s worth of introductory general chemistry at the college level, plus intriguing topics that are rarely discussed in the classroom, this amazingly comprehensive course requires nothing more advanced than high-school math. Your guide is Professor Ron B. Davis, Jr., a research chemist and award-winning teacher at Georgetown University.

We are in the midst of a global mental health crisis, and mental illnesses are on the rise. But what causes mental illness? And why are mental health problems so hard to treat? Drawing on decades of research, Harvard psychiatrist Dr. Chris Palmer outlines a revolutionary new understanding that for the first time unites our existing knowledge about mental illness within a single framework: mental disorders are metabolic disorders of the brain. Brain Energy will transform the field of mental health, and the lives of countless people around the world.

Richard Dawkins' brilliant reformulation of the theory of natural selection has the rare distinction of having provoked as much excitement and interest outside the scientific community as within it. His theories have helped change the whole nature of the study of social biology, and have forced thousands to rethink their beliefs about life.

Hilarious, fascinating, and a roller coaster of dizzying, historical what-ifs, Napoleon's Hemorrhoids is a potpourri for serious historians and casual history buffs. In one of Phil Mason's many revelations, you'll learn that Communist jets were two minutes away from opening fire on American planes during the Cuban missile crisis, when they had to turn back as they were running out of fuel. You'll discover that before the Battle of Waterloo, Napoleon's painful hemorrhoids prevented him from mounting his horse to survey the battlefield.

Astrophysicist Neil deGrasse Tyson has attracted one of the world’s largest online followings with his fascinating, widely accessible insights into science and our universe. Now, Tyson invites us to go behind the scenes of his public fame by unveiling his candid correspondence with people across the globe who have sought him out in search of answers. In this hand-picked collection of 100 letters, Tyson draws upon cosmic perspectives to address a vast array of questions about science, faith, philosophy, life, and of course, Pluto.

Welcome to the Universe is a personal guided tour of the cosmos by three of today's leading astrophysicists. Inspired by the enormously popular introductory astronomy course that Neil deGrasse Tyson, Michael A. Strauss, and J. Richard Gott taught together at Princeton, this book covers it all - from planets, stars, and galaxies to black holes, wormholes, and time travel.

How do today's most successful tech companies - Amazon, Google, Facebook, Netflix, Tesla - design, develop, and deploy the products that have earned the love of literally billions of people around the world? Perhaps surprisingly, they do it very differently from the vast majority of tech companies. In Inspired, technology product management thought leader Marty Cagan provides listeners with a master class in how to structure and staff a vibrant and successful product organization and how to discover and deliver technology products that your customers will love.

Beginning with opium, the “joy plant,” which has been used for 10,000 years, Thomas Hager tells a captivating story of medicine. His subjects include the largely forgotten female pioneer who introduced smallpox inoculation to Britain, the infamous knockout drops, the first antibiotic, which saved countless lives, the first antipsychotic, which helped empty public mental hospitals, Viagra, statins, and the new frontier of monoclonal antibodies. This is a deep, wide-ranging, and wildly entertaining book.

In The Quantum Universe, Brian Cox and Jeff Forshaw approach the world of quantum mechanics in the same way they did in Why Does E=mc2? and make fundamental scientific principles accessible - and fascinating - to everyone.The subatomic realm has a reputation for weirdness, spawning any number of profound misunderstandings, journeys into Eastern mysticism, and woolly pronouncements on the interconnectedness of all things. Cox and Forshaw's contention? There is no need for quantum mechanics to be viewed this way.

A scientist's exploration into the mysteries of the human mind. Neuroscience studies the brain, but what does science have to say about the mind? A full examination of what we mean by the term "mind" has traditionally been the province of philosophers, but what might neuroscience teach us about it? How does the mind differ from consciousness? And how do we know who we really are?

This urgent and eye-opening book makes the case that protecting humanity's future is the central challenge of our time. If all goes well, human history is just beginning. Our species could survive for billions of years - enough time to end disease, poverty, and injustice, and to flourish in ways unimaginable today. But this vast future is at risk. With the advent of nuclear weapons, humanity entered a new age, where we face existential catastrophes - those from which we could never come back.

Are you up for a trip through the ultimate neighborhood? Join astrophysicist Hugh Ross for an insider’s look at our cosmic neighborhood, where you’ll see everything from the largest-scale structure of the universe to Earth’s innermost layers. In Designed to the Core, Ross explains how the most sophisticated scientific instruments reveal exquisite “interior designs” throughout the universe that are ideally suited for human habitation here on Earth right now.

Of all the things humans rely on plants for - sustenance, beauty, medicine, fragrance, flavor, fiber - surely the most curious is our use of them to change consciousness: to stimulate or calm, fiddle with or completely alter, the qualities of our mental experience. Take coffee and tea: People around the world rely on caffeine to sharpen their minds. But we do not usually think of caffeine as a drug, or our daily use as an addiction, because it is legal and socially acceptable.

What is consciousness? Why are we here? Where did it all come from - the laws of nature, the stars, the universe? Humans have been asking these questions forever, but science hasn't succeeded in providing many answers - until now. In The Grand Biocentric Design, Robert Lanza, one of Time magazine's "100 Most Influential People", is joined by theoretical physicist Matej Pavšic and astronomer Bob Berman to shed light on the big picture that has long eluded philosophers and scientists alike.

Our understanding of cancer is slowly undergoing a revolution, allowing for the development of more effective treatments. For the first time ever, the death rate from cancer is showing a steady decline...but the “War on Cancer” has hardly been won. In The Cancer Code, Dr. Jason Fung offers a revolutionary new understanding of this invasive, often fatal disease - what it is, how it manifests, and why it is so challenging to treat.

Smart people are not only just as prone to making mistakes as everyone else - they may be even more susceptible to them. This is the "intelligence trap", the subject of David Robson's fascinating and provocative book. The Intelligence Trap explores cutting-edge ideas in our understanding of intelligence and expertise, including "strategic ignorance", "meta-forgetfulness", and "functional stupidity."

In the most famous scandal of sports history, eight Chicago White Sox players - including Shoeless Joe Jackson - agreed to throw the 1919 World Series to the Cincinnati Reds in exchange for the promise of $20,000 each from gamblers reportedly working for New York mobster Arnold Rothstein. Heavily favored, Chicago lost the Series five games to three. Although rumors of a fix flew while the series was being played, they were largely disregarded by players and the public at large.

It was a cool, quiet evening at Calumet Farm, where the most valuable racehorses—including the prolific stallion Alydar—had settled into their stalls for the evening. Alton Stone, filling in for the regular night watchman, completed his rounds at the barn. Although nothing seemed out of the ordinary, an inexplicable hunch led Stone to check on Alydar. What he found—a grievously injured horse with no discernable cause—jump-started one of the biggest mysteries to ever hit the horse racing world.

Humans have kept honey bees in hives for millennia, yet only in recent decades have biologists begun to investigate how these industrious insects live in the wild. The Lives of Bees is Thomas Seeley’s captivating story of what scientists are learning about the behavior, social life, and survival strategies of honey bees living outside the beekeeper’s hive - and how wild honey bees may hold the key to reversing the alarming die-off of the planet’s managed honey bee populations.

Your body is incredible, but it’s also out to destroy you. Your brain is like an early computer operating system, riddled with bad code, slow to load, and more likely to watch cat memes than go to sleep. You’d be a mess without your skeleton, but it can be a bony cage if you’re tortured by backaches, niggling neck pain, and knee joints that crumble under pressure. And your nose is a design disaster, getting blocked, springing leaks, and growing random tufts of hair.

Conservationist Rachel Carson spent over six years documenting the effects on DDT, a synthetic organic compound used as an insecticide, on numerous communities. Her analysis revealed that such powerful, persistent chemical pesticides have been used without a full understanding of the extent of their potential harm to the whole biota, including the damage they've caused to wildlife, birds, bees, agricultural animals, domestic pets, and even humans. An instant best seller that was read by President Kennedy during the summer of 1962, this classic remains one of the best introductions to the complicated and controversial subject.

Fatal conveniences are the toxic products we routinely use and the unhealthy things we do that our culture and corporations have made us believe are safe and necessary for living well and efficiently. These things—from deodorant, cosmetics, dental floss, and sunscreen to laundry detergent, air fresheners, carpets, and crayons to candles, tea bags, cell phones, and chewing gum—are ubiquitous in daily life . . . and they are wreaking havoc on our health and our planet.

Villains of All Nations explores the "Golden Age" of Atlantic piracy (1716-1726) and the infamous generation whose images underlie our modern, romanticized view of pirates.

By the star physicist and author of multiple #1 Sunday Times bestsellers, a major and definitive narrative work on black holes and how they can help us understand the universe.